Abstract
AbstractThe synthesis and antibacterial activity of 1‐substituted amino‐2‐fluoro‐4‐oxo‐4H‐quino[2,3,4‐i,j][1,4]benox‐azine‐5‐carboxylic acid derivatives is described. Key steps in the synthesis include carbon homologation and two intramolecular nucleophilic displacement cyclization reactions to generate the 4‐oxo‐4H‐quino[2,3,4‐i,j]‐[1,4]benoxazine‐5‐carboxylic acid nucleus.
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