Abstract

A novel method for thiazolyl-pyrazolone rings formation is established using the reaction of phenacyl bromide and thiosemicarbazide with ethyl acetoacetate in the presence of aryl aldehyde to give 4-arylidene-3-methyl-1-(4-phenylthiazol-2-yl)-1H-pyrazol-5(4H)-ones in good yields.

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