Abstract
AbstractThe synthesis of novel triaryl‐substituted 4‐(isothiazol‐3‐yl)morpholines 7 and 8, and 1‐(isothiazol‐3‐yl)piperazines 9–13 by reaction of the corresponding isothiazolium salts 5 and 6 with secondary amines in the presence of t‐BuOK in absolute THF is described. Some representatives of the isothiazoles were evaluated as inhibitors of acetylcholinesterase from Electrophorus electricus.
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