Abstract
Mannich-type Friedel-Crafts reaction between indoles and ethyl glyoxylate imines proceeded spontaneously in the absence of an acid catalyst. Ethyl α-(3-indolyl)glycinates were obtained in moderate to high yields. Reaction with (R)-α-methylbenzylamine derived imine afforded chiral α-(3-indolyl)glycinates with good diastereoselectivities (up to 96:4).
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Published version (
Free)
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
