Abstract
All available literature data on the chemical synthesis and isolation from natural sources of 3β-hydroxy-20-oxo-30-norlupan-28-oic (platanic) acid and its derivatives and their biological activity were reviewed. A one-step synthesis of platanic acid from betulin was developed. Its glycosylation by α-acetobromoglucose (ABG) catalyzed by Ag2O in various solvents such as pyridine, CH2Cl2, and their mixture was studied. The optimal synthetic schemes for platanic acid monoglucosides and diglucoside were found. NMR spectra of platanic acid and its glycosides were studied.
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