Abstract
Reaction of (aminodichlorophenoxy)acetic acids with 3,5-dichlorosalicylic acid chloride in acetonitrile produced salicylanilides containing carboxymethoxyl group in aniline fragment. The yield of the target compounds depends on the structure of the acylated amine and the order of addition of amine, acid chloride and proton acceptor. Also, the synthesis procedure of some intermediates necessary for the synthesis, in particular 2,6-dichloro-4-nitrophenoxyacetic acid methyl ester, was improved.
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