Abstract

The synthesis of a series of 3-pyrazolinyl-substituted chlorins, possessing different basic skeletons of chlorophyll degradation products such as pheophorbide-a, pyropheophorbide-a, purpurin-18, purpurin-7, purpurin-5, chlorin-p 6, and chlorin-e 6, was fulfilled from methyl pheophorbide-a by chemical modification and 1,3-dipolar cycloaddition with diazomethane. The structures of new chlorins were characterized by ultraviolet (UV), infrared (IR), 1H NMR, and mass spectra and elemental analysis.

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