Abstract
Benzophenone derivatives are reported to show biological activities such as cytotoxic activities against human oral squarnous carcinoma cells (HSC-2) and normal human gingival fibroblasts (HGF) [1], antibiotic activities against methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus faecium [2] and protein kinase C inhibitor [3].[...]
Highlights
To stirred solution of o-vanillin 2 (0.85 g, 5.64 mmol) in dry dichloromethane (40.00 mL) at 0 oC were successively added 3,4-diamino benzophenone 1 (0.60 g, 2.82 mmol) and a large excces of anhydrous MgSO4 (2.00 g, 16.67 mmol)
Schiff bases are used as ligand for complex formation of some metal ions [13]
Metal-salen complexes are used as catalysis in epoxidation of alkenes [14], asymmetric cyclopropanation [15] and highly selective PVC membrane sensors for the sulfate ion [16]
Summary
To stirred solution of o-vanillin 2 (0.85 g, 5.64 mmol) in dry dichloromethane (40.00 mL) at 0 oC were successively added 3,4-diamino benzophenone 1 (0.60 g, 2.82 mmol) and a large excces of anhydrous MgSO4 (2.00 g, 16.67 mmol). Benzophenone derivatives are reported to show biological activities such as cytotoxic activities against human oral squarnous carcinoma cells (HSC-2) and normal human gingival fibroblasts (HGF)1] ], antibiotic activities against methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus faecium [2] and protein kinase C inhibitor [3].
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