Abstract
The synthesis of a series of methylene(methylimino) (MMI) linked oligodeoxyribonucleotide dimers modified at the 2′‐position with fluoro and/or methoxy groups and their incorporation into different sequences has been accomplished. From these dimers, bis 2′‐OMe MMI dimer was selected for further studies based on its synthetic accessibility and the increased thermodynamic stability conferred upon oligonucleotides incorporating this modification. †In honor and celebration of the 70th birthday of Professor Leroy B. Townsend.
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