Abstract

9-(2-Deoxy-2-amino-β-D-arabinofuranosyl) adenine (IIIa) and guanine (IIIb) were synthesized from the corresponding azide compounds (II) obtained by nucleophilic substitution of tosyloxy groups of 2'-O-p-toluensulfonyladenosine (Ia) and guanosine (Ib), respectively. Their antitumor activity against sarcoma-180 solid tumor and cytotoxic activity against HeLa-S3 cells were determined.

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