Abstract

2-[β-(5′-halogenofur-2′-yl)vinyl]benzimidazoles (I) have been synthesized by the condensation of o-phenylenediamine with 5-halogeno-fur-2-ylacroleins or of 2-methylbenzimidazole with 5-halogenofurfurals. The methiodides of the 1-methyl-substituted derivatives ofI readily react with secondary amines (piperidine, dimethylamine)giving methiodides of 2-[β-(5′-dialkylaminofur-2′-yl)vinyl]-1-methylbenzimidazoles.

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