Synthesis of 2,3-Substituted β-N-Glycosyl Indoles through C-H Activation/Annulation Process under Rh(III)-Catalysis.

Guangkuan Zhao,Olivier Provot,Samir Messaoudi,Mouad Alami,Mingxiang Zhu

doi:10.1021/acs.orglett.9b03893

Synthesis of 2,3-Substituted β-N-Glycosyl Indoles through C-H Activation/Annulation Process under Rh(III)-Catalysis.

Guangkuan Zhao, Olivier Provot + Show 3 more

Open Access

https://doi.org/10.1021/acs.orglett.9b03893

Copy DOI

Journal: Organic letters	Publication Date: Dec 20, 2019
Citations: 13

Affiliation: University of Paris-Saclay, University of Paris-Sud, Institut Polytechnique de Paris, French National Centre for Scientific Research

#Indoles In Good Yields #Good Yields

Abstract
Full-Text PDF
Similar Papers

Abstract

An efficient and selective C-H activation method of readily available β-N-aryl glycosides with various alkynes has been established. Using [Cp*RhCl2]2 as a catalyst and AgSbF6 in DCE, this protocol proved to be general to prepare a variety of 2,3-substituted N-glycosyl indoles in good yields.

Full Text