Abstract
The fluorination of the antitumour agents VP 16-213 and podophyllotoxin using [ 18F]acetyl hypofluorite is described. Overall labeling yields of 10% and 20% respectively were obtained. The F-atom is found to be introduced into the E-moiety of the compounds, apparently without unwanted conformational changes.
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More From: International Journal of Radiation Applications & Instrumentation. Part A, Applied Radiation & Isotopes
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