Abstract
A stereo selective approach for the azasugars 1,4-dideoxy-1,4-imino- d-allitol, l-allitol, and 1,4-dideoxy-1,4-imino- d-talitol is described for different olefin compounds I derived from ( R)-2,3- O-isopropylidine glyceraldehyde, l-ascorbic acid, and d-isoascorbic acid by using vinyl Grignard addition, allylation, RCM, and dihydroxylation as the key steps.
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