Synthesis of 1‐nitro‐2‐(p‐hydroxyphenyl)[2‐3H1]ethane

Abstract

AbstractA racemic mixture of (R)‐ and (S)‐1‐nitro‐2‐(p‐hydroxyphenyl)[2‐3H1]ethane was synthesized from 1‐nitro‐2‐(p‐hydroxyphenyl)ethene by selective reduction of the olefin with sodium boro[3H]hydride. The nitroethene was obtained in one step by condensation of p‐hydroxybenzaldehyde with nitromethane. The produced racemic mixture is to be used in studies regarding the involvement of 1‐nitro‐2‐(p‐hydroxyphenyl)ethane as intermediate in the biosynthesis of tyrosine‐derived cyanogenic glucosides and glucosinolates.