Abstract
AbstractStarting from a selectively protected derivative of α,α′‐diaminosuberic acid (3) the linear protected peptide 11 has been obtained. Cyclisation to 12 followed by removal of the protecting groups by hydrogenolysis afforded the ‘dicarba’ analogue of oxytocin, 1 c, which showed about 5 IU/μmol of uterotonic activity in vitro.
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