Synthesis of 1,4‐dihydro‐4‐oxopyrrolo[1,2‐b]pyridazine‐3‐carboxylic acids and 1,4‐dihydro‐4‐oxoimidazo[1,5‐b]pyridazine‐3‐carboxylic acids as potential antibacterial agents

Abstract

AbstractTo check the antibacterial potential of two families of aza analogues of the quinolones, 1,4‐dihydro‐4‐oxopyrrolo[1,2‐b]pyridazine‐3‐carboxylic acids and 1,4‐dihydro‐4‐oxoimidazo[1,5‐b]pyridazine‐3‐carboxylic acids, we have prepared a few derivatives in theses families using N‐aminopyrrole and N‐aminoimidazole derivatives as starting building blocks and the classical pathways of the quinolone series. The compounds showed no interesting antibacterial activity.