Abstract
Benzazepinones display a wide range of pharmacological activity, and are used for treatment of heart diseases, cancer, and Alzheimer's disease. They are also found in naturally-occurring alkaloids. Furthermore, benzazepinones are used as building blocks for synthesis of benzazepines useful for treatment of various neurological conditions. Structurally analogous dibenzazepinones are also found in pharmaceutically-relevant organic molecules. Here, methods of synthesis of benzazepinones – hydroamination, carbopalladation, amidation, Friedel–Crafts alkylation, rearrangements with cycle enlargement are reviewed. How to Cite Petuskovs, A.; Shubin, K. Chem. Heterocycl. Compd. 2016 , 52 , 84. [ Khim. Geterotsikl. Soedin. 2016 , 52 , 84.] For this article in the English edition see DOI 10.1007/s10593-016-1835-5
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