Abstract
A strategy for the 1,3-dipolar cycloaddition of nitrilimines to δ-allenoates has been developed to provide various 1,3,5-trisubstituted pyrazole-4-carboxylates and pyrazole-4 -carboxamide derivatives, which have excellent anticancer effects. This protocol exhibits characteristics of good yield, mild reaction condition, facile operation process and post-processing steps.
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