Abstract

The invention relate to 1, 2-dihydroazete-3-methyl ester and a series of derivatives, which can be used to treat cardiovascular diseases and hepatitis c virus (HCV). This research mainly describe a synthesis route of the key intermediate for synthetizing Forskolin and HCV NS5B inhibitors. The synthesis routes is mainly consist of three steps of acylation, replacement and hydrolysis. This synthesis route provides some valuable references and experimental basis for the synthesis of Forskolin and HCV NS5B inhibitors.

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