Abstract
A facile method for the synthesis of a series of novel β-acylamino furans stating from renewable monosaccharide was achieved. Glucosamine hydrochloride was selectively N-acylated with acyl chlorides in methanol/triethylamine to yield N-acyl-d -glucosamines, which were subsequently converted into β-acylamino furans through dehydration and cyclization under microwave irradiation.
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