Abstract
Synthesis, neurotropic activity and SAR of new S-alkyl derivatives of 8- pyrazol-1-yl pyrano[3,4-c]pyridines
Highlights
Synthesis of pharmaceuticals for the treatment of neuropsychiatric disorders, in particular epilepsy, is a serious challenge for medicinal synthetic organic chemistry
A similar S–O Smiles rearrangement is observed in our previous work,[14] where we described the proposed mechanism of reaction
New pyrazolo substituted heterocyclic systems incorporating pyrano[3,4-c]pyridines 4a-e were synthesized by a new method and their neurotropic activity was studied
Summary
Neurotropic activity and SAR of new S-alkyl derivatives of 8- pyrazol-1yl pyrano[3,4-c]pyridines. Girolamo Cirrincione in recognition of his outstanding contributions to the fields of organic and medicinal chemistry
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