Synthesis, magnetic, spectral and antimicrobial studies on metal complexes of 4-methylphenylaminoacetoisatin hydrazone

Abstract

A new series of Mn(II), Co(II), Ni(II), Cu(II), Zn(II), Cd(II), Cr(III), Fe(III) and Cu(I) complexes of 4-methylphenylaminoacetoisatin hydrazone (HL) have been prepared and characterised The IR spectral data of the complexes indicate neutral bidentate, neutral tridentate or monobasic tridentate behaviour of the ligand depending on the metal ion. The ESR spectra of the complexes [Cu(OAc) (L)].0.5H2O, [CuCl(L)].0.5H2O, [Cr(Cl)(OH)2(HL)].0.5H2O, Co(NO3)2[(HL)2].2.5H2O and [(HL)(Mn)3(Cl)4(OH)2(H2O)6].H2O, are isotropic. However, those of [Cu(NO3)(L)].2.5H2O and [Cu(SO4)(H2O)(HL)], are anisotropic with ionic bond characters. The antibacterial and antifungal activities of the compounds show that some metal complexes exhibit a greater inhibitory effect than tetracycline (bacteria) and amphotricine (fungi).