Synthesis, luminescent properties and antibacterial activity of new pyrazoline and pyrimidine derivatives of (2<i>e</i>)-1-biphenyl-3-arylprop-2-en-1-ones

Abstract

Substituted prop-2-en-1-ones were obtained by the condensation reaction of 1-biphenyl-4-yl-ethanone with aromatic aldehydes in the presence of sodium hydroxide in an aqueous ethanol solution. Subsequent cyclization of the latter with hydrazine hydrate, phenylhydrazine, and thiosemicarbazide in an acidic medium leads to the corresponding pyrazolines. The reaction of amidine hydrochlorides with chalcones in a KOH-ethanol system leads to 2,4,6-trisubstituted pyrimidines. The luminescent and antibacterial properties of the resulting systems was studied.