Synthesis, electrochemical and anti-microbial study of 2,5-diamino benzoquinones

Abstract

Fifteen symmetric and unsymmetric 2,5-diamino benzoquinones have been synthesized and their electrochemical activity was studied by cyclic voltammetry. Presence of electron donating substituent like amino group found to shift the half wave potential towards more negative value which is more prominent in benzyl amino substituted amino benzoquinones (ABQs). All the compounds were checked for their anti-bacterial and anti-fungal activity by agar well diffusion technique. The more negative E1/2 values of benzyl amino substituted ABQs make them more active towards various bacterial and fungal speciesas is evident from MIC values.