Abstract
Magnesium oxide (MgO) and manganese oxide (MnO) nanoparticles were synthesized by chemical method and characterized. Their antioxidative and antidiabetic potential was assessed. Seven groups with eight rats per group were assigned as negative control (NC), positive control (PC), standard control (Std-C), magnesium oxide nanoparticle high dose (MgO-300) and low dose (MgO-150), manganese oxide nanoparticle high dose (MnO-30) and low dose (MnO-15) groups. Glucose levels showed an increase in PC group whereas MgO-300 group showed a maximal decrease in glucose levels (P ≤ 0.05). Insulin levels increased significantly in MgO-300 group as compared with PC group. The MnO-30 and MnO-15 groups showed a dose-dependent effect (P ≤ 0.05). A significant increase in serum paraoxonase was observed in the MgO-300 group (P ≤ 0.05). Total antioxidant capacity (TAC) and total oxidant status (TOS) indicated a significant effect exerted by MgO-300 and MgO-150 groups (P ≤ 0.05). MgO and MnO nanoparticles can potentially be an alternative for bulk supplementation for Diabetes Mellitus mangement.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
