Synthesis, crystal structures and urease inhibition of copper, nickel and zinc complexes derived from 4-chloro-2-((pyridin-2-ylmethylene)amino)phenol

Abstract

A series of copper, nickel and zinc complexes, [CuClL] (1), [CuBrL] (2), [NiL2] (3), [ZnL2] (4) and [Zn2I2L2] (5), where L is the deprotonated form of 4-chloro-2-((pyridin-2-ylmethylene)amino)phenol, have been synthesized and characterized by elemental analysis, IR and UV-Vis spectra. The structures of the complexes were further confirmed by single crystal X-ray diffraction. The Cu ions in 1 and 2 are in square planar coordination. The Ni and Zn ions in 3 and 4 are in octahedral coordination. The coordination of the Zn ions in centrosymmetric complex 5 is between square pyramidal and trigonal bipyramidal. The copper complexes have excellent urease inhibitory activity.