Synthesis, Crystal Structures, and Cytotoxicity Studies of Two Cobalt(III) and Zinc(II) Complexes Derived from 2-Ethoxy-6-[(3-methylaminopropylimino)methyl]phenol

Abstract

A new cobalt(III) complex, [CoL2]ClO4 (1), and a new zinc(II) complex, [Zn(HL)2(NCS)]NCS (2) (HL 2-ethoxy-6-[(3-methylaminopropylimino)methyl]phenol), have been synthesized and characterized by elemental analysis, IR spectra, and single crystal X-ray diffraction. In (1), the Co atom, lying on the inversion center, is six-coordinate in an octahedral coordination, with two phenolate O, two imine N, and two amine N atoms from two Schiff base ligands. In (2), the Zn atom is five-coordinate in a trigonal-bipyramidal coordination, with two imine N atoms from two Schiff base ligands and one thiocyanate N atom defining the basal plane, and with two phenolate O atoms from two Schiff base ligands occupying the axial positions. The cytotoxic activities of both complexes were evaluated.