Synthesis, crystal structures, and biological property of dinuclear oxovanadium(V) complexes derived from tridentate Schiff bases

Abstract

A pair of structurally similar dinuclear oxovanadium(V) complexes, [VO2L1]2 (I) and [VO2L2]2 (II), where L1 and L2 are the mono-anionic form of 2-[(2-isopropylaminoethylimino)methyl]-4-methylphenol (HL1) and 4-fluoro-2-[(2-isopropylaminoethylimino)methyl]phenol (HL2), respectively, have been synthesized and characterized by elemental analysis, FT-IR spectra, and single crystal X-ray determination. The crystal of I is monoclinic: space group P21/c, a = 12.528(1), b = 12.266(1), c = 9.432(1) A, β = 104.814(3)°, V = 1401.2(3) A3, Z = 2. The crystal of I is monoclinic: space group P21/n, a = 12.3128(5), b = 6.5124(3), c = 17.1272(7) A, β = 105.863(1)°, V = 1321.1(1) A3, Z = 2. The V…V distances are 3.210(1) A in I and 3.219(1) A in II. The V atoms in the complexes are in octahedral coordination. Biological assay indicates that complex II, bearing fluoro-substitute groups, has stronger antimicrobial activity against most bacteria than complex I which bearing methyl-substitute groups.