Synthesis, crystal structures and antibacterial activities of copper and nickel complexes derived from 5-bromo-2-((3-methylaminopropylimino)methyl)phenol

Abstract

Three new copper(II) and nickel(II) complexes, [Cu3L2(μ 2-NO3)2(μ 1,1-N3)2] (1), [Cu2L2(μ 1,1-N3)2]n (2) and [Ni3L2(MeOH)2(μ 2-η 1:η 1-CH3COO)2(μ 2-η 2:η 0-CH3COO)2] (3), where L = 5-bromo-2-((3-methylaminopropylimino)methyl)phenolate, have been synthesized and characterized. The complexes were characterized by elemental analyses, IR, UV–Vis spectra, molar conductivity, and single crystal X-ray diffraction. X-Ray analysis indicates that the Cu ions in 1 are in square pyramidal and octahedral coordination, and the Cu ions in 2 and the Ni ions in 3 are in octahedral coordination. The molecules of the complexes are linked through hydrogen bonds and π···π interactions. The complexes were assayed for antibacterial activities against three Gram-positive bacterial strains (Bacillus subtilis, Staphylococcus aureus, and Streptococcus faecalis) and three Gram-negative bacterial strains (Escherichia coli, Pseudomonas aeruginosa, and Enterobacter cloacae) by the MTT method.