Synthesis, crystal structure, DNA binding, and cleavage activity of butterfly-like 12-coordinate praseodymium(III) complex

Abstract

ABSTRACTThe present work demonstrates the structural characterization of the butterfly-like 12-coordinate praseodymium(III) complex with 2-formylpyridine acetylhydrazone (FPAH). The complex was crystallized in the monoclinic crystal system with space group P21/n. The X-ray diffraction analysis of the complex reveals twelve-coordinated distorted icosahedrons for the PrN4O8 chromophore defined by two neutral chelating FPAH ligands as well as three-coordinated NO3 anions. The complex has a distorted icosahedral structure. The intermolecular interactions were supported by Hirshfeld surfaces and fingerprint plots. The absorption spectral titrations of the complex with CT-DNA reveal groove binding of the complex with DNA. The complex exhibited significant DNA cleavage activity in the absence of an oxidant.