Synthesis, Crystal Structure, and Biological Activities of 2-Oxo-2-aryl-1-(1,2,4-triazol-1-yl) ethyl phenylcarbamodithioate

Abstract

The two title compounds, 2-oxo-2- p-tolyl-1-(1,2,4-triazol-1-yl) ethyl phenylcarbamodithioate(compound 3a) and 2-oxo-2- p-biphenyl-1-(1,2,4-triazol-1-yl) ethyl phenylcarbamodithioate(compound 3b), were synthesized and identified by IR, EA and 1H NMR spectra. The crystal structure of compound 3b was determined by X-ray diffraction analysis. The compound crystallized in a monoclinic system of space group P2 1/ c with M r = 398.47(C 23H 18N 4OS), a = 0.8769(2) nm, b = 1.1924(2) nm, c = 2.0440(6) nm, β = 109.66(3) °, V = 2.0126(8) nm 3, Z = 4, D c = 1.315 g/cm 3, F(000) = 832, μ = 0.183 mm -1, final R 1 = 0.0819. The biological test result shows that the two title compounds exhibit certain fungicidal activities.