Synthesis, crystal structure and antimicrobial activity of a hetero trinuclear manganese(III)-iron(II) complex derived from N,N’-bis(5-methylsalicylidene)-1,2-diaminoethane

X-M Hu,W-C Yang,L-W Xue,G-Q Zhao

doi:10.4314/bcse.v29i3.8

Abstract

A new hetero trinuclear manganese(III)-iron(II) complex, [Mn(salen)(H2O)]2[Fe(CN)6], in which salen is the dianionic form of N,N’-bis(5-methylsalicylidene)-1,2-diaminoethane, has been prepared and characterized by elemental analyses, IR, and single crystal X-ray crystallographic determination. The crystal of the complex is monoclinic: space group P21/c, a = 10.768(2), b = 14.248(3), c = 15.222(3) Å, β = 95.394(2)º, V = 2325.0(8) Å3, Z = 2, R1 = 0.0754, wR2 = 0.2366. The bis-Schiff base ligand coordinates to the Mn atom through phenolate O and imine N atoms. Each Mn atom in the complex is in octahedral coordination, with the equatorial donor atoms come from the Schiff base ligand, and with the axial donor atoms come from a water O atom and a cyanide N atom. The effects of the complex on the antimicrobial activity against Staphylococcus aureus, Escherichia coli, and Candida albicans were studied. KEY WORDS: Schiff base, Manganese(III) complex, Iron(II) complex, Heteronuclear, Crystal structure Bull. Chem. Soc. Ethiop. 2015, 29(3), 407-413.DOI: http://dx.doi.org/10.4314/bcse.v29i3.8

Highlights

Schiff bases are a kind of important ligands in coordination chemistry and have extensive application in many fields [1,2,3]
The band disappeared on complexation, and new C–O absorption band appeared at 1086 cm-1 in the spectrum of the complex, indicating that the Schiff base coordinates to the metal atom through deprotonated form
The infrared spectrum of the complex displays intense absorption band at 1615 cm-1, which can be assigned to the C=N stretching frequencies of the Schiff base ligand, whereas for the free Schiff base the corresponding absorption band is observed at higher wavenumber, 1632 cm-1

Summary

INTRODUCTION

Schiff bases are a kind of important ligands in coordination chemistry and have extensive application in many fields [1,2,3]. Schiff bases derived from aromatic carbonyl compounds have been widely studied in connection with metalloprotein models and asymmetric catalysis, due to the versatility of their steric and electronic properties. Schiff bases and their biologically active complexes have been often used as chelating ligands in the coordination chemistry of transition metals as radiopharmaceuticals for cancer targeting, agrochemicals, as model systems for biological macromolecules, as catalysts and as dioxygen carriers [4,5,6,7]. The preparation, characterization and antimicrobial activity of a new hetero trinuclear manganese(III)-iron(II) complex, [Mn(salen)(H2O)]2[Fe(CN)6], in which salen is the dianionic form of N,N’-bis(5-methylsalicylidene)-1,2-diaminoethane (H2salen), is reported

Material and methods

RESULTS AND DISCUSSION

CONCLUSION