Abstract
Ferulic acid derivatives containing the 1,3,4-oxadiazole thioether and trifluoromethyl pyrimidine have displayed a wide array of pharmacological properties of interest to both medicinal and agricultural chemistry. This study focused on the synthesis of a new compound, (E)-2-(3‑methoxy-4-((6-(trifluoromethyl)pyrimidin-4-yl)oxy)styryl)-5-((2-(trifluoromethyl)benzyl)thio)-1,3,4-oxadiazole, with a ferulic acid skeleton, was synthesized via acetylation, condensation, cyclization, etherification, and thioetherification reactions. The title compound underwent comprehensive characterization using a variety of analytical techniques to gain a thorough insight into its molecular structure and properties. The structural arrangement of the compound was validated through X-ray diffraction and density functional theory calculations, while further analysis uncovered important physical and chemical attributes like molecular electrostatic potential and vibrational absorption bands. Moreover, the antifungal efficacy of the synthesized compounds was assessed, indicating their possible application in agriculture. This research lays the groundwork for the creation of novel compounds with antifungal properties.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
