Synthesis, complexation properties, antimicrobial and anticoagulant activity of 2-{3-[4-(dimethylamino)phenyl]-1-hydroxyprop-2-en-1-ylidene}-4-nitro-1H-indene-1,3(2H)-dione

Abstract

This article presents the synthesis of a new 4-nitro-cinnamoyl derivative of 2-acyl-1,3-indandione. The resulting compound was subjected to interaction with ErCl3x6H2O, which was obtained from Er2O3 and HCl. The synthesized compounds were proven by IR and NMR spectroscopy. The spectral data clearly proves the formation of a chelate complex. A probable structural formula of the coordination compound is also proposed. The obtained compounds were used for analysis of their antimicrobial and anticoagulant activity.