Abstract
The Schiff base has been synthesized by reacting tranexamic acid with indol-3-carboxyaldehyde in the first step and then with carbon disulfide at room temperature in the second step. The homobimetallic complexes have been synthesized by reaction of Schiff base with R2SnCl2 and R3SnCl in 1 : 2 M ratio under stirring, where R = methyl, n-butyl and phenyl. The ligand and complexes have been characterized by elemental analysis, FT-IR, multinuclear NMR (1H, 13C and 119Sn) and semi-empirical study. IR data reveal the bidentate nature of the ligand. Five- or six-coordinate geometry was confirmed in solution by NMR spectroscopy. The homobimetallic complexes and ligand were tested in vitro against some pathogenic bacteria and fungi to assess their antimicrobial properties. The complexes show biological activities with few exceptions.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
