Abstract
A square planar Schiff base complex, Cu(H2L) namely N,N’-bis(4-methyl-α-salicylidene)propane-1,3-diaminecopper(II) through the condensation reaction of ligand with copper(II) acetate in the molar ratio of 1:1 in acetonitrile solvent was successfully synthesized. The obtained complex was characterized using, elemental analysis of carbon, hydrogen and nitrogen (CHN), Fourier Transform Infrared spectroscopy (FTIR) and electronic spectra of ultraviolet-visible (UV-vis) spectroscopy. FTIR confirmed the coordinates the metal ion to form mononuclear complex via tetradentate (ONNO) atoms of the phenolic group and azomethine group, respectively. The antibacterial studies of H2L and its Cu(H2L) were determined by screening the compounds against selected various Gram (+) and Gram (-) bacterial strains such as Staphylococcus epidermidis, Bacillus subtilis, Staphylococcus aureus, Vibrio cholera, Enterobacter cloacae and Escherichia coli. Indeed, preliminary results exhibited Cu(H2L) more active than the free ligand and displayed promising antibacterial activity, while no effect has been observed on strains for H2L.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
