Abstract

<p>TiO2 nanomaterials have gained much interest due to their importance of wide area application. In this study, TiO2 nanocomposites were modified with Ag NPs by the stober method. The synthesized nanocomposites were characterized by XRD, FTIR, scanning electron microscope (SEM) and energy dispersive X-ray spectroscope (EDAX), UV-DRS. Antibacterial activities were determined against the bacterial pathogens as well as in vitro cancer cell line and significant of nanocomposite’s anti-cancer activity were analyzed. Ag/TiO2 nanocomposite possesses efficient cytotoxic activity towards the A549 cell lines and can be used further for in vivo trials. Ag/TiO2 nanocomposites showed good antibacterial activity against different strains of bacteria Staphylococcus aureus, Shigella flexneri and Bacillus sp. The zone of inhibition was found to be higher in synthesized Ag/TiO2 nanocomposites as compared to standard antibiotic streptomycin.</p>

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