Synthesis, characterization, electrochemical behavior and antibacterial/antifungal activities of [Cd(l)X2] complexes with a Schiff base ligand

Abstract

A new symmetrical bidentate Schiff base ligand (L) was applied for the synthesis of some new cadmium coordination compounds with general formula of [Cd(L)X2] in which X is halide and pseudo-halide. The ligand and all cadmium complexes were characterized by some techniques such as elemental analysis, FT-IR, 1H, 13C NMR, UV-Visible and molar conductance. Electrochemical behavior of ligand and Cd(II) complexes were investigated by cyclic voltammetry method. Morphology and shape of [Cd(L)Cl2] particles were depicted by SEM. Antimicrobial properties such as antibacterial and antifungal activities of the complexes as compared with ligand were checked against three Gram-negative bacteria; Escherichia coli (ATCC 25922), Pseudomunase aeroginosa (ATCC 9027) and Salmonella Spp. and two Gram-positive bacteria; Staphylococcus aureus (ATCC 6538) and Corynebacterium renale and three fungal strains including Aspergillus Niger, Penicillium chrysogenum and Candida albicans. The results revealed appropriate antibacterial and antifungal activities for all compounds, and it was also found that the coordination of ligand to Cd (II) lead to an increase in the antimicrobial activities in most of cases.