Synthesis, Characterization, Anticancer, and Antimicrobial Activities of Bimetallic Silver and Gold Nanoparticles Synthesized Using a Purple Non‐Sulfur Bacterium Rhodopseudomonas faecalis

Abstract

AbstractOne of the recent and actively researched areas is the synthesis of bimetallic nanoparticles (BMNPs). Silver and gold BMNPs are prepared from aqueous AgNO3 and HAuCL4 as the precursors using the as prepared culture filtrate of Rhodopseudomonas faecalis as a reducing agent in aqueous medium. An ambient temperature of 25°C is maintained throughout the process, where the AgNO3 and HAuCL4 solution in 1:1 v/v is stirred continuously and culture filtrate is added. The synthesis of gold and silver nanoparticles is shown by the brown color which indicates the formation of composite nanoparticles. The characterization is done using different kinds of techniques. Synthesized nanoparticles size is in the range between 31.71 and 153.7 nm. Scanning electron microscopy (SEM) analysis shows that the nanoparticles are in small and round in shape. The anticancer and antimicrobial activities of the BMNPs are investigated. Anticancer activity of composite nanoparticles reveals that the composite nanoparticles show more cytotoxicity toward cancer cell lines HT‐29 and MCF‐7. The synthesized composite nanoparticles can be used as efficient antimicrobials and anticancer agents for diagnosis, treatment of various infections, and cancers.