Synthesis, Characterization and the Antioxidative Activity of Zinc(II), Copper(II) and Nickel(II) Schiff-base Complexes

Abstract

A naringenin Schiff-base ligand (H3L) and its three complexes, MHL . nH2O (M = Zn and Cu, n = 0.5) and NiH2LOAc . 3.5H2O, have been synthesized and characterized on the basis of elemental analysis, molar conductivity and i.r. spectrum, 1H-n.m.r., u.v. spectra and thermal analyses. In addition, the suppression ratio for O 2 −˙ (a) and the suppression ratio for OH˙(b) were determined by the use of spectrophotometric methods. IC50(a) and IC50(b) of the complexes are given. The results show that compared to the ligand, the complexes exhibit high activity in the suppression of O 2 −˙ (a) and OH˙(b).