Abstract
Objective To prepare a kind of novel artificial cartilage and study its cell biocopatibility.Methods Polyhydroxyethyl methacrylate (PHEMA),0.5％ silica and 1％-5％ hydroxyapatite were mixed to prepare the composites.The composites were characterized by Fourier transform infrared spectroscopy (FTIR),scanning electron microscopy (SEM),swelling ratio (SR) measurement and the absorption of bovine serum albumin (BSA).Results Inorganic particles were n nanoscopic diameter and uniformly dispersed on side of the matrices.The swelling ratio of hydrogels was 45％-50％.The absorption of BSA on the surface of composite membrane was about 5％,indicating the good biocompatibility.Conclusion A biocompatible organic/inorganic complex artificial cartilage was prepared. Key words: Polyhydroxyethyl methacrylate ; Hydroxyapatite ; Silica; Artificial cartilage
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