Abstract
A new Cu(II) selective phosphorescent sensor based on a cationic iridium(III) complex was synthesized and characterized. Compared with other commonly coexisting metal ions, the Ir(III) complex displayed significant phosphorescence quenching for detecting Cu2+ with a 1:1 stoichiometry in MeOH/H2O (1:1, v/v) solution. Upon addition of Cu2+, the rapid quenching of emission intensity provided a sensitive method for detection of Cu2+. The corresponding detection limit was determined to be 7.6 × 10−8 M and the association constant between the Ir(III) complex and Cu2+ was calculated to be 0.31 × 105 M−1. Luminescence imaging experiments demonstrated that this Ir(III) complex was cell permeable and suitable for monitoring intracellular Cu2+ in living Hela cells by confocal microscopy.
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