Synthesis, Characterization and Hirshfeld Surface Analysis of a 2-thiophene Acetic Acid Derivative

Abstract

N,N′-dicyclohexylcarbamoyl-2-(thiophen-2-yl)acetamide (C19H28N2 O2S), was prepared using 1,3-dicyclohexylurea. The compound has been characterized by IR, and single-crystal X-ray diffraction followed by a detailed Hirshfeld surface analysis. The compound crystallizes in the monoclinic space group P21/c, with cell parameters a = 9.0969(3) Å, b = 18.3067(5) Å, c = 11.6499(3) Å, β = 103.876(2)°, V = 1883.49(10) Å3, Z = 4. The crystal structure of the compound is stabilized by the intermolecular interactions of types N–H…O, C–H…O and intramolecular interactions of the type C–H…O.