Abstract
We here report the synthesis of new cyclopentadienyl ruthenium(II) complexes of general formula [(η5-C5H5)Ru(PP)(L)]+ (PP = two triphenylphosphine, 1,2-diphenylphosphinoethane), isolated as PF6− salts, with L being galactose and fructose carbohydrate derivative ligands, N-coordinated to the metal centre by nitrile, tetrazole and 1,3,4-oxadiazole moieties. The ten new organometallic compounds were fully characterized by FT-IR, 1H, 13C, and 31P NMR spectroscopies, and by elemental analysis. The cytotoxicity of the ruthenium(II) compounds was tested on HeLa cancer cells (cervical carcinoma), unveiling IC50 values in the low micromolar range.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
