Abstract
Heptanitrile was used in preparation azide β-lactam derivatives to produce a number of new derivatives contain tetrazole ring connected to the β-lactam moiety, which were then determined the chemical structure of prepared end products by using NMR and IR spectroscopy. The biological test against selected microorganisms showed that the majority of the end derivatives had good antifungal and antibacterial activity. The antifungal and antibacterial activity of the (t2) derivative in particular was equivalent to or even superior to that of the reference drugs Amoxicillin and Fluconazole.
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