Synthesis, characterization and biological evaluation of some metals complexes with new Azo-Schiff ligand

Abstract

In this research the ligand 5-((3-(1-((5-bromopyridin-2yl)imino)ethyl)-2-hydroxyphenyl)diazenyl)-2-phenyl-2,4-dihydro-3H-pyrazol-3-one (BHAP)was used to prepare new complexes with elements Cu(II) ,Ni(II), Pt(II),Co(II) ,Cr(III). The new ligand was analyzed by partial analysis of the elements (C.H.N). UV- visible and infrared rays(FTIR), spectroscopy H1NMR, C13NMR and mass spectrometry. The complexes were prepared after determining the optimum pH and concentration values ​​by examining the spectra (UV - Vis) of the solutions of these complexes to find out the pH (3-10), concentration (1*10 -4-5.5*10-4) and molar ratios that agree with Beer-Lambert's law. The chemical measurement of the complexes was known with respect to the ligand ratio, which was verified by spectroscopy technique, after choosing the maximum absorption of the solutions of those complexes, where the ligand ratio (1:1) was achieved for all complexes. The properties of the prepared complexes were identified by (FTIR), ultraviolet and visible rays, molar conduction, atomic absorption, magnetic sensitivity and elemental analysis techniques (C.H.N. Through the results obtained from physical, chemical and spectroscopic techniques, the geometrical shape of these complexes was suggested as octahedral. All these complexes were evaluated against two types of pathogenic bacteria (positive and negative).