Abstract
A new dye with a, heterocyclic azo-Schiff base has been produced,. synthesized is being studied 5-(((E)-4-(dimethylamino)benzylidene)amino)-2-((E)-(5-methylthiazol-2-yl)diazenyl) phenol (LH) fromareaction of 2-amino-5-methyl thiazole with (dimethylamino) benzaldehyde, 3-amino phenol. Azo-Schiff base ligand reacted and including some metal ions, such as Fe(II), Co (III), Ni(II) forming chelates complex. They characterized by various analytical techniques like UV-Visb, H1-NMR, 13C- NMR spectroscopic, Molar conductance, FT-IR, Mass spectra, X-ray and FESEM elemental analysis also, The mole ratio, according to spectral tests, is [M:L] for complexes was [1:2].. This study also included the biological activity in the case of sensitive species Antibacterials include Escherichia coli (gram negative), Streptococcus (gram positive), and Penicillium (fungal)..It has been noticed that some complexes are very effective against. Azo ligand and Co(III) Complex show cytotoxis action against human Breast cancer cell line. The findings suggested that it could be used as an anti-cancer drug in medicine and pharmacy.
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