Abstract

Peptide-oligonucleotide hybrid molecules 6 and 7 have been synthesized by on-line solid phase synthesis using allyloxycarbonyl (Alloc) side chain protection for serine. The conjugates have been characterized by ma.trix-assisted laser desorption ionization time-of-flight mass spectrometry. The interaction of conjugates 6 and 7 with a complementary sequence has been studied by absorption spectroscopy.

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