Abstract

The benzaldehyde and their derivatives have a good antimicrobial properties. Our research aim is to improve the antimicrobial effect, different derived from 3-Alkil/aril -4 triozole and metoksibenzoksi. The synthesized triazoles were characterized by spectroscopic techniques, such as, 1 H NMR, 13 C NMR, UV absorption spectra, and mass spectra (MS). We were mesured their antibacterial activities in vitro against Bacillius subtilis, Yersinia enterocolitca, Bacillus cereus, Staphlacoccus aureus, Esherichia coli, Pasterulla multicida, Klepsiella pnemonias . The synthesis of a series of etoksibenzilidenamino derived 1,2,4-triazoles has been realized with good yields using the CuAAC of a variety of alkynyl heterocycles, alkynyl carbohydrates or alkynes. The structures of the obtained compounds were confirmed by NMR spectroscopy ( 1 H and 13 C) and mass spectrometry. Overall, the molecules are not showed very antibacterial activity, but our antibiotic showed that important antibacterial activity.

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